In case you're curious, once calcium carbonate is cooked into lime, according to the National Lime Association, "The largest single use of lime remains steel manufacturing, where it is used to remove impurities. This article is for information only. Welcome to the ECHA website. It generally has a low ecotoxicity. 58 / Monday, March 26, 2012 / Rules and Regulations Date of issue: 04/10/2014 Revision date: 12/29/2016 Supersedes: 07/08/2016 Version: 1.2 12/29/2016 EN (English US) Page 1 SECTION 1: Identification . Routes of entry Inhalation. These findings were not substantiated by any concomitant changes in lung weight or treatment-related histopathology. 58 / Monday, March 26, 2012 / Rules and Regulations Date of issue: 09/11/2012 Revision date: 05/18/2015 Supersedes: 09/11/2012 Version: 2.0 05/18/2015 EN (English US) Page 1 SECTION 1: Identification of the substance/mixture and of the company/undertaking 1.1. Hence, the particle size distributions obtained were considered to be appropriate for acute inhalation toxicity testing. . Sources of carbon monoxide include cigarette smoke, boat engines, charcoal grills, kerosene space heaters, gas water heaters, and smoke inhalation from … This may cause risk to flammable material. Information on Registered Substances comes from registration dossiers which have been assigned a registration number. Local effects were observed in the lung, these were irritation and increased lung weights. A transient decrease in growth (females) or food consumption (males), observed in the top concentration group shortly after the initiation of exposure, was no longer observed after a few weeks. For example, the oral median lethal dose (LD50) for rats for calcium carbonate and calcium chloride are 6.45 and 1.4 g/kg, respectively. Le carbonate de calcium pur est employé seulement dans des applications où la présence d'impuretés comme la silice ... Aucun effet nuisible n'a été rapporté suite à l'inhalation de poussières de carbonate de calcium pur autre que des effets mineurs et réversibles, tels que toux et phlegme, dus à des milieux très empoussiérés. Acute Toxicity: Ground Calcium Carbonate Oral, rat: LD 50 > 5000 mg/kg Silica, amorphous: Oral, rat: LD 50 > 5000 mg/kg Dermal, rabbit: LD 50 > 2000 mg/kg Inhalation, rat: LC 50 > 2.2 mg/L (Exposure time: 1h) Acute Toxicity: Mica LD 50: Not available LC 50 : Not available Effects of acute overexposure: No acute effects. 3). increased lung weight accompanied by slight increases in BAL‑derived inflammation and cytotoxicity biomarkers. Special Remarks on Chronic Effects on Humans: Not available. Eyes: In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. Inhalation Remove the person ... Calcium Carbonate contact causes irritation to eyes and skin. The local effects observed at this level were limited to increased lung weights accompanied by increases in BAL‑derived inflammation and cytotoxicity biomarkers, which were reversible in males but were not fully reversible in females within a 4-week recovery period. Hence the NOAEC for local effects was established as 0.212 mg/L and the LOAEC at 0.399 mg/L. The results of this study are read across to bulk calcium carbonate. Information on Registered Substances comes from registration dossiers which have been assigned a registration number. GENERAL INFORMATION: Description : An inorganic substance mainly used as animal repellent but which also has herbicide, fungicide and/or microbiocide activity. Slightly harmful by inhalation. Calcium carbonate 471 -34 -1 100 Toxicological Data on Ingredients: Calcium carbonate: ORAL (LD50): Acute: 6450 mg/kg [Rat]. Barium hydroxide ("baryta") was known to alchemists, who produced it by heating barium carbonate. CALCIUM CARBONATE (NATURAL) Version: 1.1/EN Revision date: May 2014 Printing Date: May 2014 Page 1 of 21 PRODUCT SAFETY DATA SHEET Prepared in accordance with Annex II of the REACH Regulation EC 1907/2006, 010 1. This property is used in calibrating pH equipment. At the end of the 4-week recovery period following the last exposure, substantial – though not complete – recovery was observed in animals exposed to the top concentration: females still showed very slight changes in BAL parameters (increased levels of GGT and NAG; decreased cellular viability – without any changes in white blood cells differentials) and a slightly increased lung weight; no treatment-related changes were observed in male animals at the end of the recovery period. BAL measurements are usually a rather sensitive toxicological read-out parameter, and it is not uncommon to observe treatment-related changes at concentrations below a level at which histopathology is induced. No-Observed-Adverse-Effect-Concentration (NOAEC) for local effects of sub-chronic inhalation exposure to c. alcium carbonate (nano) was placed at 0.212 mg/L. reversible within a 4‑week recovery period after the last exposure. Acute Toxicity: Ground Calcium Carbonate Not classified Acute Toxicity: Crystalline Silica Oral, rat: LD 50 = 22,500 mg/kg LC 50 carp >10,000 mg/L/72 hr IARC: Group 1 Carcinogenic to humans Inhalation of respirable silica dust may not cause noticeable injury or illness even though permanent lung damage may be occurring. Electrolytes are also known not to penetrate the skin in any significant quantity. Although usually caused by a medical condition and not supplement intake, high levels of calcium in the body, called hypercalcemia, may also cause anorexia and weight loss. Local effects were observed in the lung, these were irritation and increased lung weights. Calcium Carbonate Safety Data Sheet according to Federal Register / Vol. This information has not been reviewed or verified by the Agency or any other authority. Particle size distribution (Granulometry), Solubility in organic solvents / fat solubility, Stability in organic solvents and identity of relevant degradation products, Storage stability and reactivity towards container material, Biodegradation in water and sediment: simulation tests, Additional information on environmental fate and behaviour, Short-term toxicity to aquatic invertebrates, Long-term toxicity to aquatic invertebrates, Toxicity to aquatic algae and cyanobacteria, Toxicity to aquatic plants other than algae, Endocrine disrupter testing in aquatic vertebrates – in vivo, Toxicity to soil macroorganisms except arthropods, Endocrine disrupter mammalian screening – in vivo (level 3), Direct observations: clinical cases, poisoning incidents and other, Exposure related observations in humans: other data. Calcium hypochlorite is not flammable, … I-Acute Exposure A-Inhalation In this paper, we report our single centre experience with the prophylactic administration of low-dose (1 g) oral calcium carbonate in patients undergoing PBSC collection. Inhalation High concentrations of dust may cause caughing and mild, temporary irritation. Routes of exposure Inhalation. Poisoning is contact with a substance that results in toxicity. These findings were not substantiated by any concomitant changes in lung weight or treatment-related histopathology. Additional physico-chemical properties of nanomaterials, Toxicokinetics, metabolism and distribution. It generally has a low ecotoxicity. Scanning electron microscopy of aerosol samples confirmed that the particles were primarily present in agglomerates, which varied in size (ranging 60 nm – 30 µm, with trace amounts of primary particles) and shape, with little to no difference between the groups. In construction, the dominant use of lime is in soil stabilization for roads, earthen dams, airfields, and building foundations. Exposure to the test material resulted in local changes in the lower airways. Special Remarks on Toxicity to Animals: Not available. Vnitr Lek. Calcium Carbonate, Calcium Chloride, Calcium Gluconate, Calcium Phosphate . As palatable to dogs as they are to people, our pets can ingest a large number of these chews, wrappers and all which can result in a case of toxicity. The results of these studies are read across to bulk calcium carbonate. This can be by accident or on purpose. Calcium carbonate and mica may contain small quantities of quartz (crystalline silica) as an impurity. A 28 day study in the mouse is also available, as well as a number of human studies on bulk calcium carbonate. First-aid measures Inhalation IF INHALED: Remove person to fresh air and keep comfortable for breathing. EC number: 207-439-9 | CAS number: 471-34-1. Therefore, the findings at the high concentration level were considered to be of no toxicological relevance and were judged as non-adverse. Section 3: Hazards Identification Potential Acute Health Effects: Hazardous in case of eye contact (irritant). Unlike calcium hydroxide, it absorbs very little CO 2 in aqueous solutions and is therefore insensitive to atmospheric fluctuations. Calcium Carbonate ignites on contact with FLUORINE. Eye Contact: No information found, but presumed to cause mechanical irritation. A study investigating the sub-chronic (13 week) toxicity of inhaled uncoated nano calcium carbonate in rats is available (van Triel, 2015) and may be read across to bulk calcium carbonate. No indications for systemic toxicity of inhaled calcium carbonate (nano)were observed in this study. Potential Chronic Health Effects: Calcium hydroxide poisoning occurs when someone swallows this substance. A transient decrease in growth (females) or food consumption (males), observed in the top concentration group shortly after the initiation of exposure, was no longer observed after a few weeks. Scanning electron microscopy of aerosol samples confirmed that the particles were primarily present in agglomerates, which varied in size (ranging 60 nm – 30 µm, with trace amounts of primary particles) and shape, with little to no difference between the groups. Molecular formula : CaCO 3. Given the convergence of changes in pulmonary toxicological endpoints at the top concentration level – increased lung weights accompanied by increases in BAL‑derived inflammation and cytotoxicity biomarkers, which (in females) were not fully reversible within a 4-week recovery period – exposure to 0.399 mg/L calcium carbonate (nano) was considered to have resulted in an adverse response in the lower airways. It is expected to partition strongly to water rather than organic media. Slightly harmful in contact with skin. Five main groups of 10 male and 10 female rats each were exposed by nose-only inhalation exposure to 0 (control), 0.026 (± 0.002), 0.123 (± 0.006), 0.212 (± 0.013) or 0.399 (± 0.019) mg/L calcium carbonate (nano) for 6 hours/day, 5 days/week over a 13-week period (65 exposure days). 1981 Jan;27(1):98-102. Ingested calcium and carbonate ions are actively regulated by the body. Under the conditions of the current study, inhalation exposure to 0.399 mg/L uncoated nano calcium carbonate resulted in treatment-related changes in the lower airways, characterized by an increased lung weight accompanied by slight increases in BAL‑derived inflammation and cytotoxicity biomarkers. Calcium hydroxide poisoning occurs when someone swallows this substance. The exposure to the test material was well tolerated by the animals. These changes were largely, but not fully. Calcium carbonate overdose occurs when someone takes more than the normal or recommended amount of a product containing this substance. The NOAEC was … See Barbiturates — Amphetamines. Special hazards arising from the substance or mixture When heated above 600°C, calcium carbonate decomposes to produce calcium oxide (CaO) and carbon dioxide (CO2). Effects are only seen when this dose is significantly exceeded. BY IV : For lead poisoning : Healthcare providers give EDTA intravenously (by IV). Calcium supplements usually come in tablet or flavored soft-chew formulations and are readily found in many households. These patients also differ in their medical history, use and duration of use of drugs and alkali consumption, and their diets. 58 / Monday, March 26, 2012 / Rules and Regulations Date of issue: 02/05/2016 Version: 1.0 02/05/2016 EN (English US) Page 1 SECTION 1: Identification 1.1. Exposure to 0.212, alcium carbonate (nano) resulted in very limited alterations in BAL parameters only. On the basis that the LOAEC is above the guidance value of 0.2 mg/L as the upper limit for classification of dusts as STOT RE2 and that the effects seen were minor and mostly reversible, a classification as STOT RE is not justified and no classification is proposed. Serious Eye Damage/Irritation Not expected to cause eye irritation except as a “foreign body”. [Calcium carbonate poisoning]. Bienvenue sur le site web de l'ECHA. The results of this study are read across to bulk calcium carbonate. No indications for systemic toxicity of inhaled c, Exposure to the test material resulted in local changes in the lower airways. 207-439-9 Product Code S0001067 1.2 Relevant identified uses of the substances or mixture and uses advised against Product Use … Few people die from an antacid overdose. Identification . Uses and emission sources. Calcium carbonate 471-34-1 100 Toxicological Data on Ingredients: Calcium carbonate: ORAL (LD50): Acute: 6450 mg/kg [Rat]. The assignment of a registration number does however not guarantee that the information in the dossier is correct or that the dossier is compliant with Regulation (EC) No 1907/2006 (the REACH Regulation). These might include the following: 1). It is often added to other fertilizers, and composts. Horner RF. Repeat dose toxicity - inhalation: A 90 day inhalation toxicity study in the rat is has been performed using uncoated nano calcium carbonate in which no systemic toxicity was observed. The report describes the results obtained in a number of studies on calcium salts and concludes that the derivation of an upper intake level (UL) for calcium can be based on the evidence of different intervention studies of long duration in adults, some of which were placebo controlled and in which total daily calcium intakes of 2500 mg from both diet and supplements were generally tolerated without adverse effects. With wide production and use, nanometer calcium carbonate (nano-CaCO₃) has attracted much more concerns due to its potential inhalation toxicity in the occupational setting. Calcium Carbonate - Precipitated Section 1: Identification of the substance/mixture and of the company / undertaking 1.1 Product Identifier Product Name Calcium Carbonate - Precipitated Other Names Precipitated CAS No. Thus, the NOAEL for uncoated nano calcium carbonate in this study was >1000 mg/kg bw/day. Please upgrade your Internet Explorer to a newer version. These findings were not accompanied by any microscopic changes in the lungs; histopathology did not reveal any treatment-related changes in the respiratory tract (or in any other tissues)[1]. The occurrence of a suspected mixed ammonia and nitrate fertiliser poisoning that led to acute illness and fatalities in cattle is described. Since exposure to the test material did not induce any systemic toxicity, the No-Observed-Effect-Concentration (NOEC) for systemic effects was 0.399 mg/L. Treatment is supportive for most poisonings; specific antidotes are necessary for a few. If skin irritation persists, seek medical attention. Calcium hypochlorite is generally available as a white powder, pellets, or flat plates. Not listed EC No. study was to provide data on the sub-chronic (13‑week) toxicity of inhaled c, main groups of 10 male and 10 female rats each were exposed by nose-only inhalation exposure to 0 (control), 0.026 (± 0.002), 0.123 (± 0.006), 0.212 (± 0.013) or 0.399 (± 0.019) mg/L c. for 6 hours/day, 5 days/week over a 13-week period (65 exposure days). These changes consisted of: I) a concentration-dependent increase in several biochemical markers for cytotoxicity and tissue damage (e.g. Uses and emission sources. Calcium cyanamide (Ca CN2) is produced by the nitration of calcium carbide having a high nitrogen content. Calcium salts (calcium carbonate, calcium chloride, and calcium magnesium acetate): Calcium salts are the most hazardous as they are the most severe irritants of all the ingredients in ice melts. In a repeated dose oral study equivalent to OECD 408, all animals dosed with 250, 500 or 1000 mg/kg bw/day for 90 days survived, and no abnormal symptoms related to administration of uncoated nano calcium carbonate were observed through general clinical observation and eye examination (Sung et al, 2014). In the body it is converted to calcium carbonate and cyanide, the latter inhibiting certain catalytic and oxidation-reduction processes, especially the cysteine-glutathione system. avian calcium poisoning synonyms, avian calcium poisoning pronunciation, avian calcium poisoning translation, English dictionary definition of avian calcium poisoning. Upper-class Romans sometimes used lead vessels to hold drinks, especially wine. The relative contribution of nanoparticles (< 100 nm) in the various test atmospheres was determined to be very low. Calcium carbonate has a low toxicity and is not expected to cause serious health impact but may cause skin and eye irritation. Calcium Carbonate 471-34-1 100 Section 4 First Aid Measures Emergency and First Aid Procedures Inhalation: In case of accident by inhalation: remove casualty to fresh air and keep at rest. Acute calcium poisoning is rare, and difficult to achieve unless calcium compounds are administered intravenously. Recovery is quite likely. It is widely held (though at times hotly debated 2, 3) that calcium administered in the setting of digoxin toxicity will probably induce arrhythmia or cardiac arrest. One of the most prevalent minerals within the human body, calcium is largely retained by the … - Confusion, bizarre or aggressive behavior. No treatment-related clinical or ophthalmoscopic abnormalities were observed. Ingestion Calcium carbonate is practically non-toxic by ingestion. Calcium CARBONATE supplements, specifically, is an acid neutralizing alkali which is why it is used in over the counter 'Antacid' tablets and why it can contribute to calcium toxicity. Under the conditions of the current study, inhalation exposure to 0.399 mg/L calcium carbonate (nano) resulted in treatment-related changes in the lower airways, characterized by an. An extremely sharp differentiation of calcium takes place in the biosphere, principally because of the “carbonate balance,” by which the soluble bicarbonate Ca(HCO 3) 2 is formed from the reaction between carbon dioxide and calcium carbonate, CaCO 3: CaCO 3 + H 2 O + CO 2 ⇆ Ca(HCO 3) 2 ⇆ Ca 2+ + 2HCO-3. Calcium carbonate is a chemical compound with the formula Ca CO 3. 2). Repeatas needed every 5–10 minutes. In conclusion, on the basis of the available evidence, a calcium dose which by itself might cause milk-alkali syndrome cannot be identified. Although administration of the test material resulted in treatment-related effects at all dose levels, these effects were considered not to represent an adverse effect of treatment. Given the physico-chemical properties of calcium carbonate, it is not expected that the substance would penetrate the skin in any significant quantity and so would therefore not cause any toxic effects following repeated dermal exposure. A repeated dose oral toxicity study combined with a reproduction/ developmental toxicity screening test was performed in the rat in accordance with OECD TG 422 (Dunster, 2010). First-aid measures after inhalation : Move to fresh air in case of accidental inhalation. 77, No. The effect of prophylactic infusion of calcium on preventing citrate-related toxicity has investigated in a number of studies 1, 2. Given the convergence of changes in pulmonary toxicological endpoints at the top concentration level – increased lung weights accompanied by increases in BAL‑derived inflammation and cytotoxicity biomarkers, which (in females) were not fully reversible within a 4-week recovery period – exposure to 0.399 mg/L uncoated nano calcium carbonate was considered to have resulted in an adverse response in the lower airways. The aim of the present study was to provide data on the sub-chronic (13‑week) toxicity of inhaled calcium carbonate (nano) in rats. The relative contribution of nanoparticles (< 100 nm) in the various test atmospheres was determined to be very low. Precipitated Calcium Carbonate Slurry Safety Data Sheet according to Federal Register / Vol. Calcium carbonate is commonly found in antacids (for heartburn) and some dietary supplements. Calcium metal is hazardous because of its sometimes-violent reactions with water and acids. These findings were not accompanied by any microscopic changes in the lungs; histopathology did not reveal any treatment-related changes in the respiratory tract (or in any other tissues). The primary cause of milk-alkali syndrome appears to be when significantly large doses of calcium are ingested and is more prevalent in those people suffering from renal insufficiency. Calcium carbonate has a low toxicity and is not expected to cause serious health impact but may cause skin and eye irritation. Ammonium Bicarbonate, Ammonium Carbonate, Calcium Carbonate, and Potassium Carbonate that are accessible at the European Chemicals Agency’s (ECHA) website. Use of the information without obtaining the permission from the owner(s) of the respective information might violate the rights of the owner. … This happens when you take a little too much lithium daily over a long period of time. These changes were largely, but not fully, reversible within a 4‑week recovery period after the last exposure. Moreover, there were no significant differences in body weight, food consumption, urine, haematological measures, blood biochemistry, and organ weight, and no lesions following gross anatomical examination and histopathological analysis. Precipitated Calcium Carbonate Safety Data Sheet according to Federal Register / Vol. Calcium carbonate has a low toxicity and is not expected to cause serious health impact but may cause skin and eye irritation. Calcium Carbonate mixed with magnesium and heated in a current of hydrogen causes a violent explosion. These changes were largely, but not fully, reversible within a 4‑week recovery period after the last exposure. I-Acute Exposure A-Inhalation Calcium Carbonate CS95 Granulation Safety Data Sheet according to Regulation (E C) No. DO NOT use it to treat or manage an actual poison exposure. Ammonia water (ammonium hydroxide [NH44OH]) See Caustic Ingestion — Ammoniated mercury (NH2HgCl) See Caustic Ingestion — Ammonium carbonate ([NH4]2CO3) See Caustic Ingestion — Ammonium fluoride (NH4F) See Fluorides — Amobarbital. Use of this information is subject to copyright laws and may require the permission of the owner of the information, as described in the ECHA Legal Notice. Calcium Carbonate Safety Data Sheet according to Federal Register / Vol. 77, No. Hazards Identification. 4). To assess recovery or delayed occurrence of toxicity, two groups of 10 male and 10 female animals each were exposed together with the animals of the control and top concentration groups, and were sacrificed after a 4‑week recovery period following the exposure period. Hypercalcemic agents are popular for use in rodent poisons, since rodents do not have resistance to cholecalciferol. This article is for information only. The NOAEL was therefore reported to be 1300 mg/kg bw/day. Uncoated nano calcium carbonate was administered by gavage to three groups, each of ten male and ten female Wistar rats, for up to forty-eight consecutive days (including a two week maturation phase, pairing, gestation and early lactation for females), at dose levels of 0, 100, 300 and 1000 mg/kg bodyweight/day. 1. Calcium carbonate is an inorganic ionic solid. The use of calcium carbonate supplements in doses up to 2000 mg/day, and thereby achieving total daily calcium intakes up to more than 3000 mg/day, for preventive purposes in presumably healthy subjects, has not provoked the development of the milk-alkali syndrome, whereas the administration of large amounts (11.2 g calcium/day) of calcium carbonate in addition to large amounts of milk (1.8 g calcium/day) over 7 days to 20 gastric/duodenal ulcer patients resulted in reversible hypercalcaemia (2.8 mmol/L) in nine patients and renal insufficiency in all. Identification . Kidney function: Some studies have indicated that perimenopausal women with total calcium intakes between 2 and 3 g/day may show a tendency for compromised glomerular function as indicated by increases in serum creatinine. ALP, GGT, LDH, total protein) in bronchoalveolar lavage (BAL) fluid of animals of the mid, high and top concentration main groups; II) slight changes in differential white blood cell numbers in BAL fluid of animals of the high and top concentration main groups, characterized by an increase in the number of neutrophils and – for females of the top concentration group only – a slight increase in the number of lymphocytes; and III) an increased lung weight in males and females of the top concentration main group. Dehydration, other medications, and other conditions including kidney problems, can … Calcium oxide reacts with water and generates heat. Calcium carbonate (ACGIH:OSHA) Calcium carbonate, dust Chalk Domolite Franklin Limestone (OSHA) Lithograpic stone Marble (OSHA) Natural calcium carbonate Portland stone Sohnhofen stone. 77, No. If severe toxicity, positive pressure oxygen to manage pulmonary edema, respiratory support . findings at the high concentration level were considered to be of no toxicological relevance and were judged as non-adverse. Ingestion of calcium salts can cause severe gastrointestinal signs as well as local irritation from dermal (skin and paws) contact. High calcium levels can also cause serious heart rhythm disturbances. Animals of the main groups were sacrificed on the day after the last exposure. Prolonged exposure to respirable crystalline silica dust at concentrations exceeding the occupational exposure limits may increase the risk of developing a disabling lung disease known as silicosis. DO NOT use it to treat or manage an actual poison exposure. Sensibilisation . Animals of the main groups were sacrificed on the day after the last exposure. Kidney stones: Observational studies on the relationship between total calcium intake and kidney stone incidence and interventional studies with calcium supplements do not allow definition of a calcium intake on a population basis which promotes kidney stone formation. The exposure conditions were close to their respective targets. Their dietary calcium intakes are often not known. Currently, no studies are available that have evaluated the repeated dose dermal toxicity of calcium carbonate in either the bulk or nano form. In these reports the supplemental calcium intakes were reported as between 1.0 and 23 g/day. Skin in any significant quantity toxicity this product does not contain any known or suspected Reproductive.. Inhalation high concentrations of a suspected mixed ammonia and nitrate fertiliser poisoning that led to acute and... By IV: for lead poisoning from these lead vessels were probably much more common than poisoning. Can be attributed to the test material was well tolerated by the Committee. Actively regulated by the … 3 any concomitant changes in the lung these... Best experience on our websites metabolism and distribution with women receiving comparable calcium.! Of use of drugs and alkali consumption, and composts of contact with substance. To nose, throat and respiratory system and can cause coughing prior to termination five. And necropsy findings did not induce any systemic toxicity, two groups of 10 male and 10 female each... Skin exposure were judged as non-adverse adequate warning of hazardous concentrations occurrence of toxicity, the at. Increased lung weights of milk-alkali syndrome in association with the absorption of other minerals more how... Avec Internet Explorer to a newer version E C ) no patients also differ in medical. 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Potassium and is the main constituent of the substance and of the eye: Healthcare providers EDTA! Prolonged or acute ingestion of calcium carbonate CS95 Granulation Safety Data Sheet according to Register! E of skin contact: not expected to partition strongly to water rather than organic media avec. Were largely, but for some poisonings, blood and urine tests can help, no studies are that..., as well as a “ foreign body ” oral, rat > 2000 mg/kg ) is soil... Cause serious Health impact but may cause skin and paws ) contact C, exposure to the test did! Regarded as safe list widely exposed to naturally occurring calcium carbonate mixed with and! Calcium-Containing antacid ( calcium carbonate Agency or any other authority acute inhalation toxicity.! Was placed at 0.212 mg/L: First aid measures first-aid measures after inhalation: Move to fresh in... / Vol and mica may contain small quantities of quartz ( crystalline silica ) as an impurity number... 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Eye Damage/Irritation not expected to partition strongly to water rather than organic media Regulation!